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Define close-up. close-up synonyms, close-up close-up translation, English dictionary definition of close-up. n. 1. A photograph or a movie shot in which the subject is tightly framed and shown at a relatively large scale. Close-up - definition of close-up by The Free Dictionary Please note: You are currently browsing img closeup celebs on twitter jennifer lawrence httptco that is 500x674px in size. This image is listed in ????? close up category. Closeup definition of closeup by The Free Dictionary, 500x674 in 49.24 KB.